Ion Chromatography Standards
Apexbio Technology LLC DTNB 69-78-3 1g
DTNB (69-78-3) is a biochemical reagent that reacts specifically with free sulfhydryl (-SH) groups It is utilized to quantitatively detect thiol groups in biological samples DTNB exerts its activity by undergoing disulfide bond cleavage upon interaction with free thiols leading to the formation of a colored derivative 5-thio-2-nitrobenzoate (TNB) which is measurable by spectrophotometry at 412 nm Based on these properties DTNB is widely applied in the quantification of reduced glutathione (GSH) and assessment of thiol levels in tissues blood and cultured cells enabling studies of oxidative stress redox state and thiol-reactive drug screening
Apexbio Technology LLC Sudan I 842-07-9 1g
Sudan I (842-07-9) is a small-molecule inhibitor targeting microbial growth notably Clostridium perfringens and Clostridium ramosum It is used to modulate bacterial physiology by altering signaling pathways involved in cell viability and replication Sudan I exerts its biological activity primarily through disruption of cellular metabolic processes essential for microbial proliferation In in vitro studies Sudan I demonstrates inhibitory activity with IC50 values typically between 10 30 M depending on the bacterial strain and experimental conditions Based on these pharmacological properties Sudan I holds research potential in microbiology investigation and antimicrobial assay development particularly for studies on microbial inhibition mechanisms and comparative efficacy testing
Apexbio Technology LLC Mepiroxol 6968-72-5 1g
Mepiroxol is a small-molecule compound characterized by its ability to form specific interactions with target proteins It engages in salt bridge interactions with arginine residues (such as Arg-153 and Arg-74) and participates in hydrogen bonding via its hydroxyl group with protein residues like Asp-50 and Gly-96 supporting enhanced binding affinity Researchers utilize Mepiroxol for investigations into protein-ligand interaction mechanisms aiding structural biology analyses and guiding drug-design efforts
Apexbio Technology LLC Oxipurinol 2465-59-0 1g
Oxipurinol (CAS 2465-59-0) is a small molecule inhibitor of xanthine oxidoreductase (XO) an enzyme integral to purine metabolism As the principal active metabolite of allopurinol oxipurinol functions as a noncompetitive XO inhibitor contributing significantly to the pharmacological effects observed with allopurinol therapy In vitro studies indicate that both allopurinol and oxipurinol demonstrate XO inhibition and exhibit free radical scavenging properties with evidence of cardioprotective effects independent of XO activity In vivo oxipurinol administration has been shown to reduce vascular free radical production in hypercholesterolemic animal models Its pharmacokinetic profile is characterized by predominant renal clearance Oxipurinol is widely utilized in research exploring oxidative stress cardiovascular physiology and disorders of purine metabolism
Apexbio Technology LLC Lisinopril 76547-98-3 1g
Lisinopril (CAS 76547-98-3) is a small molecule inhibitor of angiotensin-converting enzyme (ACE) By blocking ACE activity lisinopril reduces the formation of angiotensin II which diminishes vasoconstriction and aldosterone-mediated sodium and water retention resulting in reduced peripheral vascular resistance This compound is frequently utilized in biomedical research to investigate the pathophysiological mechanisms of hypertension congestive heart failure and cardiovascular disorders as well as to develop and validate preclinical pharmacological models related to ACE inhibition
Sigma Aldrich Fine Chemicals Biosciences Sodium chlorite | 7758-19-2 | MFCD00003478 | 1kg
Sodium chlorite | Purity: 80% | MW:90.44 | 7758-19-2 | MFCD00003478 | 1kg
Apexbio Technology LLC Coenzyme Q0 605-94-7 1g
Coenzyme Q0 (CAS 605-94-7) is a quinone derivative originally derived from cinnamon extract It modulates multiple cellular pathways by inducing apoptosis and autophagy primarily through inhibition of the HER-2/AKT/mTOR signaling cascade Additionally Coenzyme Q0 regulates transcription factors such as NF B and AP-1 enhances Nrf2 stability and mitigates inflammation and oxidative stress Its anti-angiogenic properties are mediated via downregulation of the MMP-9/NF- B pathway and upregulation of HO-1 signaling Coenzyme Q0 is widely used in basic research and drug development targeting cancer inflammation and angiogenesis-related disorders
Apexbio Technology LLC IBC 293 306935-41-1 1g
IBC 293 (CAS 306935-41-1) is a selective agonist of the G protein-coupled receptor GPR109b By activating GPR109b IBC 293 modulates specific signaling pathways involved in the regulation of lipid and glucose metabolism The compound exhibits high affinity for the human GPR109b receptor with a reported pEC50 of approximately 6 4 IBC 293 serves as a valuable research tool for elucidating GPR109b-mediated mechanisms and receptor function in the context of metabolic syndrome and cardiovascular disease models
Apexbio Technology LLC DL-Adrenaline 329-65-7 1g
DL-Adrenaline is a non-selective agonist targeting alpha- and beta-adrenergic receptors It is designed to activate these adrenergic receptors thereby modulating downstream cellular signaling pathways involved in vascular contraction cardiac stimulation and bronchodilation DL-Adrenaline exerts its biological activity primarily through adrenergic receptor activation Based on these pharmacological properties DL-Adrenaline holds research potential in the study of adrenergic receptor function and downstream signaling in cardiovascular respiratory and neurophysiological processes as well as serving as a reference molecule for experimental assays investigating receptor affinity selectivity and activation pathways